Follicular lymphoma genomics
نویسندگان
چکیده
منابع مشابه
Follicular Lymphoma
The article entitled “Renal Infiltration of Follicular Lymphoma”, written by Petkovic et al. and published in one of the recent issues of your journal, was quite interesting [1]. Here we would like to emphasize some relevant points. Extranodal disease is relatively common; any organ may be involved. The most common sites of extranodal disease include the bone marrow, skin, gastrointestinal trac...
متن کاملPathogenesis of follicular lymphoma.
Follicular lymphoma (FL) is presented as a germinal centre B cell lymphoma that is characterized by an indolent clinical course, but remains - paradoxically - largely incurable to date. The last years have seen significant progress in our understanding of FL lymphomagenesis, which is a multi-step process beginning in the bone marrow with the hallmark t(14;18)(q32;q21) translocation. The pathobi...
متن کاملConjunctival pediatric follicular lymphoma.
moderate nuclear sclerotic cataract in the right eye, and a well-centered posterior chamber intraocular lens in the left eye. No hypopyon was noted. There was a moderate vitreous haze in both eyes with a small area of retinitis along the superior temporal arcade of the left eye. Otherwise, the optic nerve, macula, and periphery were grossly normal in each eye. Given the clinical setting, a diag...
متن کاملPathology of follicular lymphoma.
Follicular lymphoma (FL) is a heterogeneous disease, and there are many different subgroups, such as in terms of age of onset, involved organ (especially extranodal sites such as gastrointestinal tract) and genetic abnormality. Grade 3B is currently regarded as a distinct entity by molecular genetic analyses, but the independence of Grade 3A remains unclear. Variations of clinical course are kn...
متن کاملFollicular lymphoma (FL)
The patients most often present widespead disease at diagnosis, with nodal and extranodal (bone marrow) involvement. Peripheral blood involvement is detectable by light microscopy in approximately 10% of the cases, but the majority of cases can be shown to have circulating malignant cells by sensitive molecular genetic methods. The disease usually runs an indolent course. Grade 3 FL may be char...
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ژورنال
عنوان ژورنال: Leukemia & Lymphoma
سال: 2020
ISSN: 1042-8194,1029-2403
DOI: 10.1080/10428194.2020.1762883